Humans spend the vast majority of their lives indoors, making architecture an undeniable and substantial actor in daily experience. Attempts to more clearly interpret the impacts of buildings, urban spaces, and the built environment on our bodies and brains is the task taken up by the Academy of Neuroscience for Architecture. The Academy’s 2016 conference recently brought together thinkers bridging the gap between cognitive neuroscience and architectural practice. Much like ANFA’s 2015 gathering in collaboration with Pratt Institute, and the 2012 ANFA conference, this year’s put interdisciplinary ideas and perspectives in conversation with one another, testifying to how a joining of diverse expertise can give way to increasingly complex understandings of spatial experience.